BUSPAR (buspirone hydrochloride) Tablets. DESCRIPTION. Buspirone hydrochloride tablets, USP are an antianxiety agent that is not chemically or pharmacologically related to the benzodiazepines, barbiturates, or other sedative/anxiolytic drugs. Buspirone, sold under the brand name Buspar among others, is a medication primarily used to treat anxiety disorders particularly general anxiety disorder. [9] [10] Benefits are support for short term use. [11] How to use Buspirone HCL. Take this medication by mouth, usually 2 or 3 times a day or as directed by your doctor. You may take this medication with or without food, but it is important to choose. The active substance is buspirone hydrochloride. Each tablet contains either 5mg or 10mg of the active substance. Each tablet contains either 5mg or 10mg of the active substance. The other ingredients are lactose monohydrate, magnesium stearate, purified talc, polyvidone K-25 and potato starch. Buspar(buspirone) Uses Buspar is prescribed for the management of anxiety disorders and short-term relief of symptoms of anxiety. It is in the class of anxiolytic drugs because of the influence it has on the neurotransmitters, especially serotonin. Though not severely addictive like other anti-anxiety medicines, it is possible to suffer from buspirone withdrawal. Buspar Withdrawal Symptoms Halting buspirone use suddenly may cause several withdrawal symptoms, including irritability, agitation, insomnia, tremors, cramps, fevers, and in severe cases, seizures. High on BuSpar: The Anti-Anxiety Med That Isn’t as Innocent as You Might Think. Buspar or buspirone is used as an anti-anxiety medication. It is considered by many to have a low risk of addiction. Hey Blueshoes, First let me say, Buspirone hydrochloride tablets USP are an antianxiety agent that is not chemically or pharmacologically related to the benzodiazepines, barbiturates, or other sedative/anxiolytic drugs. Buspirone is a prescription medication used to treat anxiety. It belongs to a group of anti-anxiety drugs called anxiolytics, but it seems to work somewhat differently than other drugs in the class. Xanax and Buspirone are two totally different types of drugs that happen to both treat a common problem, anxiety. Xanax (and all benzos) will cause physical dependence, where as Buspirone does not.